Celiac Diagnosis News

Health Calendar August 18 (The Kansas City Star)

CELIAC DISEASE: Wendell K. Clarkston discusses the diagnosis and treatment of celiac disease as well as information on long term risks associated with the disease and how it is a common cause of intestinal disorders. Sponsored by Saint Luke’s Health System. 10-11 a.m. Aug. 19, St. Luke’s South Hospital, 12300 Metcalf, Overland Park. www.saintlukeshealthsystem.org (816-932-6220, ...
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Health Calendar August 18 - Kansas City Star

Health Calendar August 18
Kansas City Star, MO - Aug 17, 2008
CELIAC DISEASE: Wendell K. Clarkston discusses the diagnosis and treatment of celiac disease as well as information on long term risks associated with the ...
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Diabetes Drug Byetta: Pancreas Risk? - MedicineNet.com

Intestinal Gluten Receptor Key to Celiac Disease Scientists ID New Genes Tied to Crohn's Disease Noninvasive Surgery Effective for Acid Reflux Gut Bacteria Fights Inflammatory Bowel Disease Advances Aid Celiac Disease Treatment, Diagnosis Want More ...
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Johnson County Community Calendar August 13-19 - Kansas City Star

Johnson County Community Calendar August 13-19
Kansas City Star, MO - Aug 15, 2008
Cash and check only. www.thebarnplayers.org (913-432-9100) CELIAC DISEASE: Discussion of the diagnosis and treatment of celiac disease as well as ...
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Johnson County Community Calendar August 13-19 - Kansas City Star

Johnson County Community Calendar August 13-19
Kansas City Star, MO - 7 hours ago
Cash and check only. www.thebarnplayers.org (913-432-9100) CELIAC DISEASE: Discussion of the diagnosis and treatment of celiac disease as well as ...
Kansas City area’s affluence runs the gamut, study finds Bizjournals.com
all 19 news articles
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Johnson County Community Calendar August 13-19 - Kansas City Star

Johnson County Community Calendar August 13-19
Kansas City Star, MO - Aug 15, 2008
Cash and check only. www.thebarnplayers.org (913-432-9100) CELIAC DISEASE: Discussion of the diagnosis and treatment of celiac disease as well as ...
LITERARY DATEBOOK Kansas City Star
all 2 news articles
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The American Journal of Gastroenterology - Medscape News

Lactulose Breath Testing Does Not Discriminate IBS Patients ... Cytokines in the Pathogenesis of Fatty Liver and Disease Progression... Adverse Events Associated With Use of Cyclosporine in Patients With IBD... Systematic Four-Quadrant Biopsy Detects ...
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Diagnostic pitfalls and therapeutic strategies in the treatment of pancreatic duct haemorrhage

Haemorrhage via the pancreatic duct, a rare cause of upper gastrointestinal bleeding (GIB), often poses a diagnostic dilemma. We analysed our experience with 10 patients (8 men, 2 women; mean age 44 years, range 34 – 62) treated during a 12 year period. All had a history of alcohol abuse and presented with major upper GIB requiring a median of 8 units (range 2 – 40) blood, transfusion. Nine had upper abdominal pain at the time of admission and nine had a history of pancreatitis. Upper gastroduodenal endoscopy (median 4; range 1 – 9), was diagnostic in only one. Side-viewing endoscopy showed bleeding from the pancreatic duct in 7 of 8 patients. Visceral aneurysms were demonstrated in 7 of 9 patients in whom coeliac angiography was carried out: (splenic artery 4, gastroduodenal artery 2, and pancreaticoduodenal artery 1). Two of 4 selective embolisations were successful. Six patients underwent distal pancreatectomy, 1 had gastroduodenal artery ligation and 1 died of coagulopathy following a total pancreatectomy. Pancreatic duct haemorrhage should be considered in patients with unexplained recurrent upper GIB, alcohol abuse and epigastric pain, particularly in those with established chronic pancreatitis. Selective angiography is essential for diagnosis and management. For bleeding sites in the head of the pancreas, embolisation should be attempted to avoid major resection. Distal pancreatectomy is preferred for splenic artery lesions. (Source: HPB Surgery)

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Recent advances in refractory coeliac disease: a review.

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Recent advances in refractory coeliac disease: a review.

Histopathology. 2008 Aug 11;

Authors: Ho-Yen C, Chang F, van der Walt J, Mitchell T, Ciclitira P

Recent advances in refractory coeliac disease: a reviewCoeliac disease (CD) is an immune-mediated disease of the small intestine caused by intolerance to gluten. Removal of gluten from the diet results in a return to normal health for the majority of patients. A significant proportion of patients do not respond to a gluten-free diet and are considered to be suffering from refractory coeliac disease (RCD). Two types of RCD are now recognized: type 1 RCD is characterized by a polyclonal population of intraepithelial lymphocytes (IELs) with a normal immunophenotype, and type 2 RCD shows monoclonal IELs with an aberrant immunoprofile. Patients with RCD have a high risk of complications such as ulcerative jejunitis (UJ) and enteropathy-type T-cell lymphoma (ETTL). RCD2 may represent an early stage in the development of overt lymphoma. The diagnosis of RCD, therefore, has important implications, but remains a challenging area. In this paper we review the latest developments in RCD, including the diagnostic approach and a discussion of the key clinical, histological, immunohistochemical and molecular features of RCD and its complications.

PMID: 18700844 [PubMed - as supplied by publisher]

[Celiac News] [diagnosis] a rapid antibody test had high specificity

[diagnosis] a rapid antibody test had high specificity but low sensitivity for diagnosing coeliac disease
            

 (Source: Evidence-Based Medicine)
            

http://ebm.bmj.com/cgi/content/full/13/4/118?rss=1
            
Read more [Sensible Celiac Forum]

Endoscopic Biopsy Specimens Needed to Confirm Diagnosis of Celiac ... - Medscape (subscription)

Endoscopic Biopsy Specimens Needed to Confirm Diagnosis of Celiac ...
Medscape (subscription) - Aug 6, 2008
Celiac disease, a prevalent food hypersensitivity disorder, is an autoimmune disorder of the small intestine that occurs in genetically predisposed ...
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Endoscopic Biopsy Specimens Needed to Confirm Diagnosis of Celiac ... - Medscape (subscription)

Endoscopic Biopsy Specimens Needed to Confirm Diagnosis of Celiac ...
Medscape (subscription) - Aug 6, 2008
Celiac disease, a prevalent food hypersensitivity disorder, is an autoimmune disorder of the small intestine that occurs in genetically predisposed ...
Read more [Google: Celiac News]

Number of Endoscopic Biopsy Specimens Needed to Confirm a Diagnosis of ... - Medscape News

Celiac disease, a prevalent food hypersensitivity disorder, is an autoimmune disorder of the small intestine that occurs in genetically predisposed individuals and results in a small intestinal inflammatory reaction to gluten proteins (wheat, barley ...
Read more [MSN News - Celiac Disease]

New Trends In Celiac Disease - Boston Channel.com

New Trends In Celiac Disease
Boston Channel.com,  USA - Aug 5, 2008
By Julia Cruz Robert Stanhope calls his diagnosis with celiac disease “a blessing.” For years the 43-year old suffered intestinal problems that left him ...
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New Trends In Celiac Disease - Boston Channel.com

New Trends In Celiac Disease
Boston Channel.com,  USA - Aug 5, 2008
By Julia Cruz Robert Stanhope calls his diagnosis with celiac disease “a blessing.” For years the 43-year old suffered intestinal problems that left him ...
Read more [Google: Celiac News]

[antegrade aortomesenteric revascularisation originating from the supracoeliac aortic segment - a promising surgical option in chronic ischaemia of the visceral arteries.]

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[Antegrade aortomesenteric revascularisation originating from the supracoeliac aortic segment - a promising surgical option in chronic ischaemia of the visceral arteries.]

Zentralbl Chir. 2008 Aug;133(4):380-5

Authors: Halloul Z, Eder F, Wolff S, Tautenhahn J, Meyer F

INTRODUCTION: Ischaemia of the visceral arteries is considered to be an extraordinary challenge in the interdisciplinary therapeutic management. AIM AND METHOD: Using a case series of patients with chronic ischaemia of the visceral arteries, our diagnostic and therapeutic experience was analysed with regard to postoperative quality of life (increase of body weight, frequency in daily diarrhoea), perioperative morbidity and hospital mortality in dependence on the type of surgical reconstruction of the visceral arteries. RESULTS: During a time period of 2 years, 3 patients (male / female = 1 : 2; mean age, 61.7 years) underwent surgical interventions on the visceral arteries from a total of 1118 vascular interventions (main indication revealed by colonoscopy and pathohistology of mucosal biopsy: ischaemic colitis). In all cases, symptomatology was affected by abdominal angina. Duplex sonography, angiography, and multislice CT scan revealed the combination of an occlusion of the coeliac trunk and of the superior mesenteric artery by atherosclerosis in 2 cases. In the remaining case, there was an isolated occlusion at the origin of the superior mesenteric artery. For revascularisation, the aortomesenteric reconstruction was subdivided according to the: i) target vessel: - combination of revascularised common hepatic artery and superior mesenteric artery (n = 1) with an autologous Y-vein bypass ("reversed technique"), - exclusive revascularisation of the superior mesenteric artery (n = 2) - prosthetic bypass; ii) origin of the bypass: - from the supracoeliac aortic segment (antegrade) n = 3 (primarily in patients 1 and 3; as a redo operation in patient 2); - from the infrarenal segment (retrograde) n = 1 (initial surgical intervention in patient 2) using an autologous venous bypass. In all cases, a significant improval of the quality of life was observed as indicated by an increase of body weight (n = 3; + no further abdominal angina) and primary wound healing in all 3 cases (hospital mortality, 0). CONCLUSION: Chronic ischaemia of the visceral arteries is characterised by an increasing incidence and a stealthy onset and requires an interdisciplinary approach to find the correct diagnosis using all available diagnostic procedures including sufficient periodic follow-up investigations. We favour the antegrade aortomesenteric revascularisation from the supracoeliac aortic segment as a promising surgical option in chronic ischaemia of visceral arteries.

PMID: 18702026 [PubMed - in process]

[Celiac News] [diagnosis] a rapid antibody test had high specificity

[diagnosis] a rapid antibody test had high specificity but low sensitivity for diagnosing coeliac disease
            

 (Source: Evidence-Based Medicine)  MedWorm Sponsored Message: Find out how you can get your message across here by sponsoring this MedWorm news feed.
            

http://ebm.bmj.com/cgi/content/full/13/4/118?rss=1
            
Read more [Sensible Celiac Forum]

[Celiac News] Microscopic enteritis: novel prospect in coeliac disease diagnosis

Microscopic enteritis: novel prospect in coeliac disease clinical and immuno-histogenesis evolution in diagnostic and treatment strategies.
            

Related Articles
        Microscopic enteritis: Novel prospect in coeliac disease clinical and immuno-histogenesis Evolution in diagnostic and treatment strategies.
        Dig Liver Dis. 2008 Jul 24;
        Authors:  Rostami K, Villana...
Read more [Sensible Celiac Forum]

[diagnosis] a rapid antibody test had high specificity but low sensitivity for diagnosing coeliac disease

(Source: Evidence-Based Medicine)
Read more [Medworm Coeliac Disease]

Microscopic enteritis: novel prospect in coeliac disease clinical and immuno-histogenesis evolution in diagnostic and treatment strategies.

Related Articles

Microscopic enteritis: Novel prospect in coeliac disease clinical and immuno-histogenesis Evolution in diagnostic and treatment strategies.

Dig Liver Dis. 2008 Jul 24;

Authors: Rostami K, Villanacci V

The diagnosis of coeliac disease has traditionally depended on symptoms and intestinal biopsies; nowadays, the diagnosis has been expanded to include an array of serological markers and subtle microscopic lesions. The most important advance in classifying mucosal lesions in coeliac disease was forwarded by Marsh (1992), who provided the biological explanation of how the small bowel reacts to a variety of environmental antigenic challenges including gluten. In the modified version of this classification (Arnhem 1998-1999) autoantibodies have integrated into Marsh's histopathological scheme. As a large part of the coeliac 'iceberg' remains unrecognised, the difficulties in diagnosis continue to challenge clinicians and researchers. Advances in immuno-histochemistry and discovery of the other sensitive markers have acquainted us with so-called Microscopic enteritis, the distinctive subtle abnormalities behind the atypical gluten sensitivity symptoms that often remain unrecognised. Current diagnostic pathways do not always include facilities for looking for this common histological feature in atypical cases. This is essential since improving of the detection rate has been shown to be directly proportional to recognition of cases with milder or minimal mucosal abnormalities. In this revision, we will define and characterise microscopic enteritis as the entity behind a wide range of unexplained gastrointestinal symptoms. Screening for this subtle and distinctive presentation in small bowel pathology will open a new prospect in recognising the most common but unrecognised atypical forms of symptomatic gluten related enteropathies.

PMID: 18657490 [PubMed - as supplied by publisher]