Medical Research | All About Celiac - information on celiac disease

Alba Therapeutics initiates enrollment in Phase IIb celiac disease study (Pharmaceutical Business Review)

Thu, 13 Nov 2008 04:42:41 -0600

Alba Therapeutics, a clinical-stage biopharmaceutical company, has announced that for the first time, a European patient with active celiac disease has been enrolled in its clinical trial to investigate a treatment for the disease.

Alba Therapeutics Announces Enrollment of Its First European Patient in Global Phase IIb Study of Larazotide Acetate ... (PR Newswire via Yahoo! Finance)

Tue, 11 Nov 2008 19:22:00 -0600

Alba Therapeutics Corporation announced today that for the first time, a European patient with active celiac disease has been enrolled in its clinical trial to investigate a treatment for the disease.

Celiacs support group meets Monday - Argus Leader

Fri, 07 Nov 2008 09:32:00 -0600

The Sioux Falls Area Celiacs Support Group will meet 7 p.m. Monday at the VA Medical Center. Dr Cristina Hill Jensen will discuss basics of celiac disease and a new study that Avera Health is participating in regarding treatment. For information ...

Histological abnormalities of the small bowel mucosa in cirrhosis and portal hypertension.

Thu, 06 Nov 2008 22:00:00 -0600

CONCLUSION: This study provides evidence for the lack of villus atrophy in patients with cirrhosis and portal hypertension, and supports the continuous reliance on the Marsh criteria when the diagnosis of coeliac disease is to be made in the presence of cirrhosis. PMID: 19009654 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)

Reduced diversity and increased virulence-gene carriage in intestinal enterobacteria of children with coeliac disease

Mon, 03 Nov 2008 22:00:00 -0600

Conclusion: This study has demonstrated that virulence features of the enteric microbiota are linked to coeliac disease. (Source: BMC Gastroenterology)

Celiacs support group meeting planned - Argus Leader

Mon, 03 Nov 2008 10:12:00 -0600

The Sioux Falls Area Celiacs Support Group will meet 7 p.m. Nov. 10 at the VA Medical Center. Dr Cristina Hill Jensen will discuss basics of celiac disease and a new study that Avera Health is participating in regarding treatment. For information ...

Increased superoxide levels in ganglia and sympathoexcitation are involved in sarafotoxin 6c-induced hypertension

Sun, 02 Nov 2008 22:00:00 -0600

Endothelin (ET) type B receptors (ETBR) are expressed in multiple tissues and perform different functions depending on their location. ETBR mediate endothelium-dependent vasodilation, clearance of circulating ET, and diuretic effects; all of these should produce a fall in arterial blood pressure. However, we recently showed that chronic activation of ETBR in rats with the selective agonist sarafotoxin 6c (S6c) causes sustained hypertension. We have proposed that one mechanism of this effect is constriction of capacitance vessels. The current study was performed to determine whether S6c hypertension is caused by increased generation of reactive oxygen species (ROS) and/or activation of the sympathetic nervous system. The model used was continuous 5-day infusion of S6c into male Sprague-Dawl...

A blinded pilot comparison of capsule endoscopy and small bowel histology in unresponsive celiac disease

Fri, 31 Oct 2008 01:17:13 -0500

This study compares video capsule endoscopy (VCE) with histological specimens of proximal small bowel in patients with celiac disease who have failed to respond to a gluten-free diet. Patients with nonresponsive celiac disease underwent capsule endoscopy, and concordance between endoscopy and histology was then calculated using the kappa statistic. In 19 patients, endoscopy videos were reported as normal in ten (53%) case, as having mild changes in three (16%) cases, and as having moderate-severe changes in six (31%) cases. Two (11%) had acute ulcers. No small bowel tumors were seen. Endoscopy demonstrated concordance with histological changes in 14 of the 18 patients with histology available (78% concordance). The kappa statistic suggested a substantial degree of concordance between...

Current Perspectives in IBS and Chronic Constipation - Medscape (subscription)

Thu, 30 Oct 2008 15:26:31 -0500

Current Perspectives in IBS and Chronic Constipation
Medscape (subscription) - Oct 30, 2008
The most common organic diseases identified in IBS patients in this study were colitis and celiac disease, although these were not more prevalent than in ...

Sammy’s Woodfired Pizza announces gluten-free options - Pizza Marketplace

Thu, 30 Oct 2008 10:20:00 -0500

Gluten, primarily found in wheat products, is highly intolerable to sufferers of celiac disease, a digestive disorder which damages the small intestine. A study conducted at University of Maryland found that one in 133 Americans has celiac disease ...

Duodenal bulb biopsies in celiac disease: a multicenter study.

Tue, 28 Oct 2008 04:38:47 -0500

Page: 618DOI: 10.1097/MPG.0b013e3181677d6eAuthors: Bonamico, Margherita *; Thanasi, Enina *; Mariani, Paolo *; Nenna, Raffaella *; Luparia, Rita Pia Lara *; Barbera, Cristiana +; Morra, Isabella +; Lerro, Pietro +; Guariso, Graziella ++; De Giacomo, Costantino [S]; Scotta, Serenella [P]; Pontone, Stefano ||; Carpino, Francesco **; Magliocca, Fabio Massimo **; and the Societa Italiana di Gastroenterologica, Epatologia, e Nutrizione Pediatrica (Source: Journal of Pediatric Gastroenterology and Nutrition)

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CDC says child food allergies are increasing (The Union Democrat)

Mon, 27 Oct 2008 17:49:32 -0500

The incidence of food allergies among children has increased in the last decade, according to a recently-released study.

CDC says child food allergies are increasing - Union Democrat

Mon, 27 Oct 2008 17:18:00 -0500

The incidence of food allergies among children has increased in the last decade, according to a recently-released study. The Centers for Disease Control and Prevention reports, from 1997 to 2007, the number of young people who had a food or digestive ...

[original articles] investigation of molecular markers in the diagnosis of refractory coeliac disease in a large patient cohort

Sun, 26 Oct 2008 22:00:00 -0500

Conclusions: This study supports the use of phenotypic and T cell clonality investigations in identifying patients with true rCD. (Source: Journal of Clinical Pathology)

Protective effects of glycyrrhizin in a gut hypoxia (ischemia)-reoxygenation (reperfusion) model

Sat, 25 Oct 2008 02:36:36 -0500

Conclusions This study demonstrates that glycyrrhizin exerts multiple protective effects in splanchnic artery occlusion–reperfusion shock. Content Type Journal ArticleCategory OriginalDOI 10.1007/s00134-008-1334-yAuthors Rosanna Di Paola, IRCCS Centro Neurolesi “Bonino-Pulejo” Messina ItalyMarta Menegazzi, University of Verona Biochemistry Division, Department of Neuroscience and Vision Verona ItalyEmanuela Mazzon, IRCCS Centro Neurolesi “Bonino-Pulejo” Messina ItalyTiziana Genovese, IRCCS Centro Neurolesi “Bonino-Pulejo” Messina ItalyConcetta Crisafulli, Policlinico Universitario Department of Clinical and Experimental Medicine and Pharmacology, Torre Biologica 98123 Messina ItalyMartina Dal Bosco, IRCCS Centro Neurolesi “Bonino-Pulejo” Messina ItalyZ...